Could My Medical Condition Be Contributing to My Anger?

June 20, 2025by Elise

Could My Medical Condition Be Contributing to My Anger?

Anger is a natural emotion — it can be a healthy way to express frustration or pain. But when it starts to erupt frequently or feels difficult to control, it might be worth asking: could something else be going on beneath the surface?

In some cases, medical conditions or medications may be contributing factors to irritability and rage.

Below are a few health-related reasons that could be influencing your mood — and how to recognise them.

Dementia and Anger

As certain types of dementia, including Alzheimer’s and Lewy Body Dementia, progress, individuals may become more prone to anger. Frustration caused by confusion, communication difficulties, or physical discomfort can lead to sudden outbursts. For caregivers, recognising that this anger may stem from the condition rather than the person’s character can be a helpful starting point for managing these moments compassionately.

Side Effects from Anxiety Medications or Sleeping Pills

Some medications, such as benzodiazepines prescribed for anxiety disorders or insomnia, may have rare but serious side effects — including aggression. People with a predisposition to impulsivity may be especially sensitive to this. If you’ve recently started a new medication and noticed mood changes, speak to your doctor about possible alternatives.

Autism and Emotional Regulation

For individuals on the autism spectrum, anger can appear suddenly and intensely, sometimes triggered by sensory overload, stress, or changes in routine. Difficulties with communication can also fuel frustration. Part of the therapeutic process often involves helping individuals identify triggers, build emotional awareness, and develop coping strategies to manage these responses in healthier ways.

Cholesterol Medication and Mood Changes

Statins, used to lower cholesterol, have been associated in some studies with an increase in irritability or aggression. This may be linked to lower serotonin levels, which can affect mood. While these medications can be essential for heart health, it’s important to monitor how they make you feel emotionally, too.

Depression and Irritability

Depression doesn’t always look like sadness. For many — especially men — it can manifest as irritability or even bursts of anger. These outbursts may be signs of underlying despair, and both therapy and medication can help address the root causes.

The Emotional Weight of Diabetes

A diagnosis like diabetes can bring a flood of emotions, including anger and fear. Additionally, low blood sugar levels may lead to increased irritability, as the body’s stress and blood sugar regulation systems are closely linked. Managing diabetes effectively can also support more stable moods.

Epilepsy and Emotional Outbursts

Although it’s uncommon, some people with epilepsy may experience aggressive behaviour following a seizure. Anti-seizure medications can also affect mood, particularly in children. Counselling can offer a space to work through the emotional impact of living with epilepsy and help develop better coping mechanisms.

Liver Function and Personality Changes

The liver plays a role in filtering toxins from the body. In severe liver disease or failure, the resulting buildup of toxins can affect brain function — a condition known as hepatic encephalopathy. This can cause shifts in mood, including anger, confusion, and personality changes.

Hormonal Fluctuations: PMS and Menopause

Hormonal changes — such as those occurring before a menstrual period or during menopause — can cause significant shifts in mood. In cases of PMDD (premenstrual dysphoric disorder), irritability may be especially pronounced. These changes often relate to fluctuating levels of estrogen, progesterone, and serotonin.

Stroke and Emotional Changes

After a stroke, individuals may experience mood changes, including increased irritability. If the stroke affects the parts of the brain responsible for regulating emotion, behavioural changes are common. These shifts can be difficult for loved ones to witness but are often a normal part of recovery.

Hyperthyroidism and Mood Swings

An overactive thyroid (hyperthyroidism) leads to an excess of thyroid hormone, which can speed up many of the body’s processes — including emotional responses. Anxiety and irritability are common symptoms, but this condition is treatable with medication.

Wilson’s Disease

This rare condition causes copper to build up in the liver and brain. When the part of the brain related to personality is affected, it can cause severe mood swings, including increased anger or agitation. Diagnosis and treatment are essential.

When to Seek Help

If you suspect that a medical issue or treatment may be influencing your anger, it’s important to talk with your doctor. Managing your physical health is a vital step toward managing emotional wellbeing.

Therapy can also help you develop tools to better understand and regulate your emotions. At Kevin & Elise Fourie Counselling Psychologists, we support individuals dealing with a wide range of emotional and mental health challenges — including anger. Together, we can help you find healthier ways to cope and thrive.

Helpful Ways to Manage Anger:

  • Practice deep breathing and calming techniques
  • Express your emotions in constructive ways
  • Keep a journal of your triggers and reactions
  • Learn healthy assertiveness skills
  • Try to find humour in difficult situations
  • Seek support from friends, family, or a therapist

If you’re struggling with irritability or emotional regulation and want to explore the deeper causes, we’re here to help.

Reach out today to take the next step on your path to better mental and emotional health.

📞 Tel: (012) 348-1342
📱 WhatsApp: 063 676 3422
📧 Email: admin@fourie-psych.com